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NAD+

BATCH

PURITY

99% HPLC

  • CAS #:
  • 53-84-9
  • Formula:
  • C21H27N7O14P2
  • M.W.:
  • 663.43 g/mol

NAD+

Cellular RepairLongevity

$198.00

Volume Pricing Guide

QUANTITY PRICE PER
1 $198.00
2 - 4 $178.20
5 - 9 $168.30
10 - 14 $158.40
15 - 19 $148.50
20 + $138.60
Only the lyophilized product is provided. All supplies sold separately. For research use only.

Summary

NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme that plays a central role in cellular energy production, DNA repair, and overall metabolic health. By supporting mitochondrial function and activating sirtuins, NAD+ enhances cellular repair mechanisms, combats oxidative stress, and promotes longevity. With a foundational role in nearly all cellular processes, NAD+ is a powerful therapeutic option for energy restoration, anti-aging, and recovery optimization.

Description & Pharmacodynamics

NAD+ functions as an essential cofactor in redox reactions, facilitating the transfer of electrons during cellular energy production. This process fuels the mitochondria, the powerhouse of the cell, enabling efficient ATP generation¹. Beyond energy metabolism, NAD+ acts as a substrate for enzymes like sirtuins and PARPs, which regulate gene expression, DNA repair, and cellular resilience to stress².

As NAD+ levels decline with age, mitochondrial dysfunction, increased oxidative damage, and impaired cellular repair are common consequences³. Supplementing with NAD+ replenishes intracellular levels, restoring metabolic efficiency, enhancing mitochondrial biogenesis, and promoting healthy aging⁴. Furthermore, NAD+ supports neuroprotection and may improve cognitive function by optimizing neuronal energy metabolism and reducing neuroinflammation⁵.

Research Insights

Energy Restoration and Metabolic Optimization

    • Key Findings: NAD+ enhances mitochondrial function, boosting ATP production and reducing fatigue¹,².
    • Mechanisms: Facilitates redox reactions and improves mitochondrial biogenesis¹,².
    • Applications: Chronic fatigue syndrome, athletic performance, and metabolic disorders.

Cellular Repair and Longevity

    1. Key Findings: NAD+ promotes DNA repair, activates sirtuins, and mitigates oxidative damage, extending cellular lifespan²,³.
    2. Mechanisms: Serves as a substrate for PARPs and sirtuins, facilitating genomic stability and stress resistance³,⁴.
    3. Applications: Anti-aging therapies, oxidative stress reduction, and recovery from illness or injury.

Neuroprotection and Cognitive Health

    1. Key Findings: NAD+ supports neuronal energy production, reduces neuroinflammation, and enhances synaptic plasticity⁵.
    2. Mechanisms: Optimizes mitochondrial function and reduces oxidative stress in the brain⁵.
    3. Applications: Neurodegenerative diseases, cognitive decline, and mental clarity improvement.

Structure

  • Molecular Formula: C₂₁H₂₇N₇O₁₄P₂
  • Molecular Weight: ~663.43 Da
  • PubChem CID: 120554

Citations for NAD+

  1. Martens, C.R. et al. “NAD+ Augmentation Improves Mitochondrial Function and Metabolic Efficiency.” (2018).
  2. Verdin, E. et al. “The Role of NAD+ in Cellular Energy Homeostasis.” (2020).
  3. Imai, S. et al. “NAD+ and Sirtuins in Aging and Longevity.” (2016).
  4. Sinclair, D. et al. “The Role of NAD+ in DNA Repair and Genomic Stability.” (2019).
  5. Lin, M.T. et al. “NAD+ and Neuroprotection in Aging Brains.” (2017).

**Note:** This product is intended for research purposes only and not for human consumption. Always consult with a healthcare professional before starting any new supplement or research product.

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