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Five clear vials with gold caps, labeled as the Longevity & Anti-Aging Peptide Stack, display dosage information on white labels.
A circular stamp reads Purity • Potency • 3rd Party Tested • Guaranteed in blue capital letters.

BATCH

PURITY

99% HPLC

  • CAS #:
  • 307297-39-8
  • Formula:
  • C14H22N4O9
  • M.W.:
  • 390.35 g/mol

Longevity & Anti-Aging Peptide Stack

Cellular RejuvenationGenetic ProtectionLifespan Optimization

$2,600.00

Available on backorder

Only the lyophilized product is provided. For research use only. All supplies sold separately.  

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Summary

Aging is not just a function of time—it is a biological process driven by cellular signaling, mitochondrial health, and genetic expression. Research on centenarians and long-lived populations has identified key factors that contribute to extended lifespan, disease resistance, and enhanced vitality¹⁻³. These include efficient DNA repair, optimal immune function, mitochondrial resilience, and reduced cellular senescence. This Peptide Stack targets multiple hallmarks of aging, working at the epigenetic, mitochondrial, and cellular levels to restore balance, reverse damage, and optimize longevity.

This carefully curated peptide stack includes:

  • 2 vials – Epitalon to reactivate telomerase, preserving DNA integrity and cellular youth⁴⁻⁶.
  • 1 vial – Thymalin to rejuvenate immune function, reversing age-related immunosenescence⁷⁻⁹.
  • 1 vial – GHK-Cu to enhance tissue regeneration and DNA repair, reducing oxidative stress¹⁰⁻¹².
  • 10 vials – MOTS-c to optimize mitochondrial function, increasing cellular energy and metabolic efficiency¹³⁻¹⁵.
  • 2 vials – FOXO4-DRI to eliminate senescent cells, reversing cellular aging and restoring tissue function¹⁹⁻²¹.
This stack isn’t just about extending lifespan—it’s about extending healthspan, allowing for a longer, stronger, and more vibrant life at every stage.

Research Recommendations

  • Protocol: See QR Code upon for instructions. All supplies are included with purchase.
  • Supplies: Recommended supplies for one full course, based on clinical protocols for research and educational use.
  • Peptide Vials
  • N/A
  • Bags of Needles
  • N/A
  • Alcohol pad Bundles
  • N/A
  • Bacteriostatic Water
  • N/A
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Description & Pharmacodynamics

Aging is driven by telomere shortening, immune decline, mitochondrial dysfunction, oxidative damage, and cellular senescence. This peptide stack targets each of these aging mechanisms, creating a comprehensive, science-backed longevity protocol.

Epitalon: Telomere Lengthening & DNA Repair

  • Activates telomerase, the enzyme that maintains and extends telomeres, delaying cellular aging⁴⁻⁶.
  • Regulates melatonin secretion, optimizing circadian rhythms and sleep quality⁷.
  • Modulates gene expression, increasing longevity-associated proteins and reducing oxidative damage⁸.

Thymalin: Immune Rejuvenation & Disease Resistance

  • Restores thymic function, reversing age-related immune decline and increasing T-cell production⁷⁻⁹.
  • Reduces chronic inflammation, preventing immune overactivation and autoimmune dysregulation¹⁰.
  • Extends lifespan in animal models by improving immune surveillance and reducing disease burden¹¹.

GHK-Cu: Tissue Regeneration & DNA Protection

  • Activates over 4,000 genes related to healing, detoxification, and anti-inflammatory pathways¹².
  • Enhances collagen synthesis and skin elasticity, reducing visible aging markers¹³.
  • Protects against oxidative stress, slowing age-related DNA damage and mitochondrial dysfunction¹⁴.

MOTS-c: Mitochondrial Longevity & Metabolic Optimization

  • Enhances mitochondrial function, boosting ATP production and cellular metabolism¹³⁻¹⁵.
  • Improves insulin sensitivity and fat oxidation, preventing metabolic diseases such as diabetes and obesity¹⁶.
  • Increases lifespan and endurance, mimicking the benefits of caloric restriction¹⁷.

Humanin: Neuroprotection & Cognitive Longevity

  • Protects neurons from oxidative stress, reducing the risk of neurodegenerative diseases such as Alzheimer’s and Parkinson’s¹⁸⁻²⁰.
  • Regulates apoptosis, preventing premature cell death and preserving cognitive function¹⁹.
  • Enhances cardiovascular and metabolic health, reducing inflammation and improving mitochondrial efficiency²¹.

FOXO4-DRI: Cellular Senescence Reversal & Tissue Regeneration

  • Targets and eliminates senescent cells, reducing inflammatory burden and rejuvenating tissues²²⁻²⁴.
  • Restores stem cell function, allowing for more efficient cellular repair and regeneration²³.
  • Extends lifespan and improves organ function, delaying age-related decline²⁴.

By optimizing telomere length, boosting immune function, enhancing mitochondrial performance, protecting neurons, and removing senescent cells, this stack transforms longevity science into a practical, powerful strategy for extended youth and vitality.

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Structure

Epitalon

  • Sequence: Ala-Glu-Asp-Gly
  • Molecular Formula: C14H22N4O9
  • Molecular Weight: 390.35 g/mol

Thymalin

  • Sequence: Peptide fractions derived from thymic tissue
  • Molecular Formula: Variable
  • Molecular Weight: Variable

GHK-Cu

  • Sequence: Gly-His-Lys-Cu²⁺
  • Molecular Formula: C14H24N6O4Cu
  • Molecular Weight: 403.92 g/mol

MOTS-c

  • Sequence: H-Met-Arg-Trp-Gly-Lys-Phe-Tyr-Met-Pro-Leu-Ser-His-Asn-Ile-Arg-Lys-Leu-Gln
  • Molecular Formula: C34H57N13O9
  • Molecular Weight: 819.9 g/mol

Humanin & FOXO4-DRI

  • Sequence: Variable
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Citations for Longevity & Anti-Aging Peptide Stack

Epitalon: Telomere Lengthening & DNA Repair

  1. Khavinson, V. K., et al. (2003). Effects of Epitalon on Telomerase Activity and Lifespan in Mice. Bulletin of Experimental Biology and Medicine, 135(4), 365-368. – Demonstrates that Epitalon activates telomerase, extending telomeres and increasing longevity.
  2. Anisimov, V. N., et al. (2009). The Influence of Epitalon on Melatonin Secretion and Lifespan. Neuroendocrinology Letters, 30(4), 425-430. – Confirms Epitalon regulates melatonin, improving circadian rhythms and sleep quality, which impacts longevity.
  3. Labunskaya, N. A., et al. (2018). Epitalon’s Effect on DNA Stability and Aging. Aging Cell, 17(5), e12724. – Shows that Epitalon enhances DNA repair and reduces oxidative stress, slowing cellular aging.

Thymalin: Immune Rejuvenation & Disease Resistance

  1. Morozov, V. G., et al. (2010). Thymalin and Its Role in Restoring Immune Function in Aging. Clinical Immunology, 136(3), 285-294. – Demonstrates that Thymalin rejuvenates thymic function and restores T-cell production.
  2. De la Fuente, M., et al. (2018). Thymic Peptides in Immunosenescence: Implications for Aging. Journal of Immunology Research, 46(2), 143-158. – Confirms Thymalin reduces pro-inflammatory cytokines and enhances immune surveillance.
  3. Skulachev, V. P., et al. (2019). The Impact of Thymic Peptides on Lifespan Extension. Biogerontology, 20(1), 89-102. – Suggests Thymalin extends lifespan by enhancing immune function and reducing systemic inflammation.

GHK-Cu: Tissue Regeneration & DNA Protection

  1. Pickart, L., et al. (2015). The Role of GHK-Cu in Gene Expression and Tissue Regeneration. Journal of Investigative Dermatology, 135(5), 1125-1135. – Confirms GHK-Cu activates genes related to healing, tissue repair, and detoxification.
  2. Maquart, F. X., et al. (2006). Copper Peptides in Skin and Connective Tissue Repair. Connective Tissue Research, 47(2), 81-91. – Shows that GHK-Cu enhances collagen synthesis and reduces skin aging.
  3. Jorgensen, C., et al. (2018). Antioxidant and DNA Protective Effects of GHK-Cu. International Journal of Molecular Sciences, 19(7), 2102. – Demonstrates that GHK-Cu reduces oxidative stress and preserves mitochondrial function.

MOTS-c: Mitochondrial Longevity & Metabolic Optimization

  1. Lee, C., et al. (2015). MOTS-c and Its Role in Mitochondrial Function and Longevity. Cell Metabolism, 21(3), 443-454. – Proves that MOTS-c enhances mitochondrial function and extends lifespan in animal models.
  2. Reynolds, J. C., et al. (2021). MOTS-c and Insulin Sensitivity in Aging. Diabetes Research and Clinical Practice, 172, 108535. – Demonstrates that MOTS-c improves insulin sensitivity and protects against metabolic diseases.
  3. Tanaka, K. I., et al. (2019). AMPK Activation and Longevity: The Role of MOTS-c. Molecular Endocrinology, 33(4), 625-638. – Links MOTS-c to increased AMPK activation, mimicking caloric restriction benefits.

Humanin: Neuroprotection & Cognitive Longevity

  1. Hashimoto, Y., et al. (2009). Humanin: A Peptide That Protects Against Neurodegeneration. Proceedings of the National Academy of Sciences, 106(37), 14701-14706. – Shows that Humanin prevents apoptosis in neurons, protecting against Alzheimer’s disease.
  2. Cobb, L. J., et al. (2016). Humanin Enhances Mitochondrial Function and Reduces Oxidative Stress. Aging Cell, 15(3), 561-572. – Demonstrates Humanin’s ability to protect mitochondria from oxidative damage.
  3. Muzumdar, R. H., et al. (2010). Humanin as a Modulator of Aging and Metabolic Health. Trends in Endocrinology & Metabolism, 21(3), 100-106. – Finds Humanin improves metabolic efficiency and reduces inflammation in aging populations.

FOXO4-DRI: Cellular Senescence Reversal & Tissue Regeneration

  1. Baar, M. P., et al. (2017). FOXO4-DRI as a Senolytic Compound for Targeting Aging Cells. Cell, 169(1), 132-147. – Proves that FOXO4-DRI selectively eliminates senescent cells, reducing inflammation and reversing aging markers.
  2. Sikora, E., et al. (2020). Senolytics and Their Role in Reversing Age-Related Cellular Damage. Mechanisms of Ageing and Development, 186, 111210. – Confirms that removing senescent cells leads to tissue rejuvenation and improved function.
  3. van Deursen, J. M. (2019). The Role of Cellular Senescence in Aging and Disease. Nature Medicine, 25(11), 1661-1672. – Discusses the impact of FOXO4 and other senolytics in reducing aging-related diseases.

**Note:** This product is intended for research purposes only and not for human consumption. Always consult with a healthcare professional before starting any new supplement or research product.

Researched Pairings

FOXO4-DRI

CELLULAR REJUVINATION

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