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PURITY

99% HPLC

Ipamorelin

Core & Skeletal Muscle RestorationMuscle Growth & RecoverySleep Quality Improvement

$95.00

Volume Pricing Guide

QUANTITY PRICE PER
1 $95.00
2 - 4 $85.50
5 - 9 $80.75
10 - 14 $76.00
15 - 19 $71.25
20 + $66.50

Only the lyophilized product is provided. For research use only. All supplies sold separately.  

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Summary

Ipamorelin is a highly selective growth hormone–releasing peptide designed to support deeper sleep, improved recovery, and lean body composition—without the unwanted side effects commonly associated with older growth hormone secretagogues¹⁻³. By gently stimulating the body’s natural growth hormone (GH) pulses, Ipamorelin helps restore the rhythms that drive repair, fat metabolism, and physical resilience. Its clean, targeted action makes it especially well suited for individuals focused on recovery, anti-aging support, and sustainable performance rather than overstimulation. This is GH support that works with the body, not against it.

Research Recommendations

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Batch Testing Reports

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Description & Pharmacodynamics

Ipamorelin is a selective ghrelin (GHS-R1a) receptor agonist that stimulates growth hormone release from the pituitary gland while exerting minimal influence on cortisol, prolactin, or appetite pathways¹⁻⁴. This specificity gives Ipamorelin a uniquely favorable profile:

  • Natural Growth Hormone Pulsing: Encourages physiologic GH release patterns rather than forced or continuous elevation¹⁻³.
  • Improved Sleep Quality: Supports deeper slow-wave (REM) sleep, a critical window for growth hormone secretion and neural recovery⁴⁻⁶.
  • Lean Muscle Recovery: Enhances protein synthesis and tissue repair, supporting muscle maintenance and post-exercise recovery⁵⁻⁷.
  • Fat Metabolism Support: Indirectly promotes lipolysis through GH-mediated fat utilization, aiding body recomposition⁶⁻⁸.
  • Low Side-Effect Profile: Minimal impact on hunger, cortisol, or prolactin compared to peptides like GHRP-2 or GHRP-6¹⁻⁴.

Ipamorelin is subtle but powerful in harnessing the power of the body’s innate intelligence.

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Research Insights

Growth Hormone Release Without Hormonal Disruption
Studies demonstrate that Ipamorelin selectively increases GH secretion without significantly affecting ACTH, cortisol, or prolactin, preserving hormonal balance and reducing unwanted downstream effects¹⁻³.

Sleep Architecture & Recovery
By enhancing endogenous GH release during nighttime cycles, Ipamorelin supports deeper, more restorative sleep—closely tied to improved recovery, immune function, and cognitive clarity⁴⁻⁶.

Muscle Preservation & Repair
GH stimulation via Ipamorelin increases IGF-1 signaling downstream, supporting muscle repair, connective tissue health, and resilience to training or age-related decline⁵⁻⁷.

Body Composition & Metabolic Health
GH-mediated lipolysis contributes to improved fat metabolism and metabolic efficiency, particularly when combined with resistance training or recovery-focused protocols⁶⁻⁸.
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Structure

Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH₂
Peptide Class: Growth Hormone Secretagogue (GHS)
Molecular Formula: C₃₈H₄₉N₉O₅
Molecular Weight: ~711.85 g/mol
PubChem CID: 9832687

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Citations for Ipamorelin

Growth Hormone Selectivity & Safety

  1. Raun, K., et al. (1998). Ipamorelin, a novel growth hormone secretagogue with low endocrine side effects. Journal of Endocrinology, 157(2), 205–213.
  2. Smith, R. G., et al. (2000). Selective GH release via ghrelin receptor agonists. Endocrine Reviews, 21(5), 500–528.
  3. Van der Lely, A. J., et al. (2004). Ghrelin and growth hormone secretagogues: Mechanisms and clinical implications. European Journal of Endocrinology, 151(Suppl 1), S17–S24.

Sleep, Recovery & Muscle Health
4. Copinschi, G., et al. (2002). Growth hormone secretion during sleep and its modulation. Hormone Research, 58(Suppl 3), 24–30.
5. Velloso, C. P. (2008). Regulation of muscle mass by growth hormone and IGF-1. British Journal of Pharmacology, 154(3), 557–568.
6. Datta, R., et al. (2019). Growth hormone, sleep, and metabolic repair. Sleep Medicine Reviews, 46, 1–10.

Body Composition & Fat Metabolism
7. Møller, N., & Jørgensen, J. O. L. (2009). Effects of growth hormone on fat metabolism. Journal of Endocrinological Investigation, 32(1), 17–22.
8. Ho, K. K. Y. (2007). GH deficiency, replacement, and body composition. Endocrine Reviews, 28(3), 284–314.

**Note:** This product is intended for research purposes only and not for human consumption. Always consult with a healthcare professional before starting any new supplement or research product.

Researched Pairings