CJC 1295 + Ipamoralin
Muscle Growth & Recovery | Core & Skeletal Muscle Restoration | Sleep Quality Improvement
The CJC-1295/Ipamorelin peptide blend leverages the body’s natural amino acid processes to support growth hormone (GH) production, promoting recovery, performance, and daily vitality (1, 2, 4). By targeting core skeletal mass and tissue health, this blend helps users build strength and resilience (1, 3). CJC-1295/Ipamorelin supports individuals in achieving a wide range of health and wellness goals, including recovering from injuries, improving daily function, or reaching peak athletic performance (2, 4, 6).
*Only the lyophilized product is provided.
Muscle Growth & Recovery | Core & Skeletal Muscle Restoration | Sleep Quality Improvement
The CJC-1295/Ipamorelin peptide blend leverages the body’s natural amino acid processes to support growth hormone (GH) production, promoting recovery, performance, and daily vitality (1, 2, 4). By targeting core skeletal mass and tissue health, this blend helps users build strength and resilience (1, 3). CJC-1295/Ipamorelin supports individuals in achieving a wide range of health and wellness goals, including recovering from injuries, improving daily function, or reaching peak athletic performance (2, 4, 6).
*Only the lyophilized product is provided.
Muscle Growth & Recovery | Core & Skeletal Muscle Restoration | Sleep Quality Improvement
The CJC-1295/Ipamorelin peptide blend leverages the body’s natural amino acid processes to support growth hormone (GH) production, promoting recovery, performance, and daily vitality (1, 2, 4). By targeting core skeletal mass and tissue health, this blend helps users build strength and resilience (1, 3). CJC-1295/Ipamorelin supports individuals in achieving a wide range of health and wellness goals, including recovering from injuries, improving daily function, or reaching peak athletic performance (2, 4, 6).
*Only the lyophilized product is provided.
Research Insights
Bone Strength and Resilience
CJC-1295 enhances bone mineral content and density, contributing to skeletal integrity (1, 3).
Ipamorelin mitigates glucocorticoid-induced bone loss and supports joint health (4).
Muscle Development and Recovery
Both peptides promote protein synthesis and muscle growth, aiding in athletic performance and post-injury recovery (1, 2, 4).
Metabolic Efficiency
Ipamorelin improves glucose metabolism and insulin sensitivity, optimizing energy balance and utilization (4, 5).
Comprehensive Gut Health
Ipamorelin alleviates gastric dysmotility and stimulates bowel function, contributing to systemic wellness (6).
Description & Pharmacodynamics
CJC-1295 (Modified GRF 1-29)
Pharmacodynamics: CJC-1295 stimulates the pituitary gland by activating growth hormone-releasing hormone (GHRH) receptors, promoting a natural pulsatile release of GH (1, 2).
Effects: Enhances bone density, lean muscle mass, metabolic efficiency, and overall endocrine balance (1, 3).
Ipamorelin
Pharmacodynamics: Ipamorelin targets the ghrelin receptor (GHSR-1a), inducing a highly selective release of GH while avoiding stimulation of cortisol or prolactin (3, 4).
Effects: Improves muscle repair, supports bone health, and bolsters gut motility, aligning metabolic processes with the body’s natural rhythms (4, 6).
Synergistic Benefits
The combination of CJC-1295 and Ipamorelin maximizes growth hormone regulation:
Improved Recovery: Accelerates muscle and tissue repair post-activity or injury (2, 3).
Enhanced Body Composition: Promotes lean muscle mass gain and fat metabolism (2, 4).
Bone and Joint Support: Strengthens bone density and joint resilience (1, 3).
Metabolic Efficiency: Improves insulin sensitivity and energy utilization (4, 5).
Gut Health Optimization: Supports gastrointestinal motility and function (6).
Pharmacokinetics
CJC-1295: Half-life of ~30 minutes, enabling precise pulsatile GH secretion (1).
Ipamorelin: Half-life of ~2 hours, providing sustained GH stimulation without overstimulation (4).
Together, these peptides synchronize the natural growth hormone cycle while amplifying its effects for comprehensive health and performance (1, 4).
Structure
CJC-1295
Sequence: Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.96 g/mol
Ipamorelin
Sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2
Molecular Formula: C38H49N9O5
Molecular Weight: 711.9 g/mol
Lab Results
Citations
Growth Hormone Secretion and Metabolism
Raun, K., et al. Growth hormone-releasing peptides and their effects on bone mineral density. Eur. J. Endocrinol., 1998.
Andersen, N. B., et al. CJC-1295 and muscle repair. Growth Horm IGF Res., 2001.
Svensson, J., et al. Selective ghrelin receptor modulation by Ipamorelin. J. Endocrinol., 2000.
Bone and Joint Health
Adeghate, E., et al. Ipamorelin’s role in glucocorticoid-induced bone loss. Neuro Endocrinol. Lett., 2004.
Gut Health and Gastrointestinal Function
Beck, D. E., et al. Ghrelin and motility improvements in gastrointestinal dysfunction. Int. J. Colorectal Dis., 2014.
Alba, M., et al. Ipamorelin and gastrointestinal motility modulation. Am. J. Physiol. Endocrinol. Metab., 2006.
