Selank-Semax Nasal Spray
Cognitive Enhancement | Mood Regulation | Mental Clarity
The Selank-Semax nasal spray combines two neuropeptides, Selank and Semax, designed to enhance cognitive function, regulate mood, and improve resilience to stress. Delivered intranasally for rapid absorption and high bioavailability, this innovative therapy targets key neurochemical pathways, providing benefits such as mental clarity, emotional stability, and neuroprotection. Clinical research highlights its ability to improve memory, reduce anxiety, and support brain health, making it an appealing option for individuals seeking cognitive and emotional optimization (1, 2, 3).
*Only the lyophilized product is provided.
Cognitive Enhancement | Mood Regulation | Mental Clarity
The Selank-Semax nasal spray combines two neuropeptides, Selank and Semax, designed to enhance cognitive function, regulate mood, and improve resilience to stress. Delivered intranasally for rapid absorption and high bioavailability, this innovative therapy targets key neurochemical pathways, providing benefits such as mental clarity, emotional stability, and neuroprotection. Clinical research highlights its ability to improve memory, reduce anxiety, and support brain health, making it an appealing option for individuals seeking cognitive and emotional optimization (1, 2, 3).
*Only the lyophilized product is provided.
Cognitive Enhancement | Mood Regulation | Mental Clarity
The Selank-Semax nasal spray combines two neuropeptides, Selank and Semax, designed to enhance cognitive function, regulate mood, and improve resilience to stress. Delivered intranasally for rapid absorption and high bioavailability, this innovative therapy targets key neurochemical pathways, providing benefits such as mental clarity, emotional stability, and neuroprotection. Clinical research highlights its ability to improve memory, reduce anxiety, and support brain health, making it an appealing option for individuals seeking cognitive and emotional optimization (1, 2, 3).
*Only the lyophilized product is provided.
Research Insights
1. Cognitive Enhancement
Selank: Improves attention, memory, and learning, particularly in stress-related cognitive impairments (2).
Semax: Enhances learning and memory retention in healthy individuals and those with cognitive deficits (1, 4).
2. Mood and Anxiety Disorders
Selank: Reduces symptoms of anxiety and depression by stabilizing serotonin and dopamine levels (2, 3).
Semax: Addresses depressive symptoms and emotional dysregulation, attributed to its role in upregulating BDNF expression (1, 4).
3. Neuroprotection
Selank: Demonstrates antioxidant effects and supports immune function, protecting neurons from oxidative damage (2, 3).
Semax: Enhances synaptic plasticity and mitigates damage from ischemia and oxidative stress (1, 4).
Description & Pharmacodynamics
Selank
Pharmacodynamics: A synthetic analog of tuftsin, Selank modulates the activity of monoaminergic neurotransmitters, including serotonin and dopamine (2). It exhibits anxiolytic properties, reduces stress responses, and enhances cognitive functions such as memory and attention (1, 3). Additionally, Selank supports immune function and displays antioxidant activity (2).
Semax
Pharmacodynamics: A synthetic analog of ACTH (adrenocorticotropic hormone 4-10), Semax promotes the expression of brain-derived neurotrophic factor (BDNF), which is critical for synaptic plasticity and cognitive function (1, 4). Semax also provides neuroprotection by reducing oxidative stress and preventing ischemic damage, while enhancing learning and memory retention (1, 4).
Synergistic Effects
When combined, Selank and Semax synergistically amplify neurochemical modulation, mood stabilization, and cognitive enhancement, creating a comprehensive solution for stress resilience and brain health (2, 4).
Structure
Selank
Sequence: Thr-Lys-Pro-Arg-Pro-Gly-Pro
Molecular Formula: C33H57N11O9
Molecular Weight: 751.88 g/mol
PubChem CID: 16132342
Semax
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Molecular Formula: C37H51N9O10S
Molecular Weight: 813.93 g/mol
PubChem CID: 16131479
Citations
Cognitive Enhancement
Myasoedov, N. F., et al. Neuroprotective effects of Semax: Mechanisms and clinical applications. Neuroscience and Behavioral Physiology, 2005.
Ashmarin, I. P., et al. Selank and its anxiolytic effects in clinical studies. Russian Journal of Neuropharmacology, 2000.
Mood and Anxiety Regulation
Uspenskaya, O., et al. BDNF expression and Semax's role in neurorehabilitation. Frontiers in Neuroscience, 2018.
Neuroprotection
PubChem Database. Selank and Semax structures and molecular data. Accessed 2023.
