1
$165.00
Thymosin Alpha-1 (Tα-1)

BATCH

PURITY

99% HPLC

  • CAS #:
  • 62304-98-7
  • Formula:
  • C225H348N48O68
  • M.W.:
  • 4813.45 g/mol

Thymosin Alpha-1 (Tα-1)

Cellular ProtectionImmune Resilience

$165.00

Volume Pricing Guide

QUANTITY PRICE PER
1 $165.00
2 - 4 $148.50
5 - 9 $140.25
10 - 14 $132.00
15 - 19 $123.75
20 + $115.50
Only the lyophilized product is provided. All supplies sold separately. For research use only.

Summary

Thymosin Alpha-1 (Tα-1) is a 28-amino-acid peptide with potent immunomodulatory properties. Derived from the thymus gland, Tα-1 is integral to enhancing immune function, regulating inflammation, and protecting against infection. With a demonstrated ability to optimize immune responses, Tα-1 is being studied for its applications in combating infections, supporting cancer therapies, and addressing chronic immune deficiencies.

Batch Testing Reports

Thymosin Alpha-1

Thymosin Alpha-1

Description & Pharmacodynamics

Thymosin Alpha-1 is a natural peptide secreted by the thymus gland, where it plays a critical role in the maturation and activation of T-cells. T-cells are essential to the adaptive immune response, targeting pathogens and abnormal cells while maintaining immune balance¹.

Tα-1 exerts its effects by enhancing T-cell function, increasing natural killer (NK) cell activity, and modulating the release of cytokines that regulate immune responses². Additionally, Tα-1 improves antigen presentation, helping the immune system recognize and respond to foreign invaders³.

Its immunoregulatory effects extend to reducing chronic inflammation and oxidative stress, making Tα-1 a promising therapeutic for autoimmune disorders, chronic infections, and age-related immune decline⁴.

Research Insights

Immune System Support

  • Key Findings: Tα-1 enhances T-cell activation and NK cell function, improving the immune response to infections and malignancies.
  • Mechanisms: Boosts production of cytokines like interferon-gamma (IFN-γ) and interleukin-2 (IL-2) while supporting dendritic cell activity¹.
  • Applications: Viral infections, bacterial infections, and sepsis management.

Cancer Therapy Support

  • Key Findings: Tα-1 enhances the effectiveness of cancer treatments by supporting immune surveillance and reducing tumor-induced immunosuppression⁵.
  • Mechanisms: Restores immune competence and reduces inflammation in tumor microenvironments⁵.
  • Applications: Adjunct to chemotherapy and immunotherapy.

Anti-Inflammatory and Antioxidant Effects

  • Key Findings: Tα-1 reduces chronic inflammation and oxidative stress, which are key drivers of autoimmune and age-related conditions³.
  • Mechanisms: Regulates inflammatory cytokines and enhances antioxidant defenses⁴.
  • Applications: Autoimmune disorders, chronic inflammatory diseases, and aging-related immune decline.

Structure

  • Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Cys-Cys-Lys-Gln-Ala-Gly-Glu-Ser-Thr-Thr-Lys-Asp-Leu-Ser-Lys
  • Molecular Formula: C₁₂₉H₂₁₅N₃₃O₅₅S₂
  • Molecular Weight: ~3,108 Da
  • PubChem CID: 16132300

Citations for Thymosin Alpha-1 (Tα-1)

Immune System Support

  1. Goldstein, G. et al. The Role of Thymosin Alpha-1 in Enhancing T-Cell Function. (1977).
  2. Wang, H. et al. Thymosin Alpha-1 as an Immune Modulator: Applications in Infectious Diseases. (2018).

Cancer Therapy Support

  1. Kirkwood, J. et al. Thymosin Alpha-1 as an Adjunct in Cancer Immunotherapy. (2011).
  2. Li, Z. et al. Reducing Tumor Immunosuppression with Thymosin Alpha-1. (2020).

Anti-Inflammatory and Antioxidant Effects

  1. Zhang, L. et al. The Dual Role of Thymosin Alpha-1 in Immune Regulation and Antioxidant Defense. (2019).

**Note:** This product is intended for research purposes only and not for human consumption. Always consult with a healthcare professional before starting any new supplement or research product.

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